食品安全情報blog過去記事

はてなダイアリーにあった食品安全情報blogを移行したものです

EFSAは「一般機能」健康強調表示に関する最初の一連の意見を発表

EFSA

EFSA delivers its first series of opinions on ‘general function’ health claims
1 October 2009
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902914361.htm
NDAパネルは欧州委員会や加盟国が作成した「一般機能」健康強調表示リストに関する最初の一連の意見を発表した。
ビタミンやミネラルや繊維、脂肪、炭水化物、プロバイオティック細菌、植物性物質など200以上の食品や食品成分に関連する523の健康強調表示について科学的助言を提供する。評価の結果約1/3は健康強調表示を支持する科学的根拠があるというもので、主にビタミンやミネラル、食物繊維、コレステロール濃度を維持するための脂肪酸、虫歯予防のための砂糖無しチューインガムなどである。根拠がないとされた原因の約半分はその主張の根拠となる物質についての情報がないためである。プロバイオティック細菌や植物成分などがそうであった。問題とされている物質の明確な定義がなければNDAパネルは科学的根拠が評価できない。
以下NDAパネルの指令No 1924/2006　13(1)条に関連する意見
日付はすべて1 October 2009

  • カルシウムと骨と歯の健康、筋機能と神経伝達、血液凝集、エネルギーを発生する代謝、消化管酵素の機能、正常血圧維持に関する健康強調表示の実証に関する意見

Scientific Opinion on the substantiation of health claims related to calcium and maintenance of bones and teeth (ID 224, 230, 231, 354, 3099), muscle function and neurotransmission (ID 226, 227, 230, 235), blood coagulation (ID 230, 236), energy-yielding metabolism (ID 234), function of digestive enzymes (ID 355), and maintenance of normal blood pressure (ID 225, 385, 1419) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902905713.htm
正常血圧維持を除く因果関係は確立されている。強調表示をするには一食あたりのカルシウム含量が基準以上であること。
正常血圧維持については根拠は不十分である。

  • フッ素と歯のミネラル化と骨の維持

Scientific Opinion on the substantiation of health claims related to fluoride and maintenance of tooth mineralisation (ID 275, 276) and maintenance of bone (ID 371) pursuant to Article 13(1) of Regulation
(EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902905726.htm
歯については確立されている、骨については確立されていない。

Scientific Opinion on the substantiation of health claims related to magnesium and electrolyte balance (ID 238), energy-yielding metabolism (ID 240, 247, 248), neurotransmission and muscle contraction including heart muscle (ID 241, 242), cell division (ID 365), maintenance of bone (ID 239), maintenance of teeth (ID 239), blood coagulation (ID 357) and protein synthesis (ID 364) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902905925.htm
正常な血液凝固以外の項目については因果関係が確立されている

Scientific Opinion on the substantiation of health claims related to vitamin B12 and red blood cell formation (ID 92, 101), cell division (ID 93), energy-yielding metabolism (ID 99, 190) and function of the immune system (ID 107) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
1 October 2009
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902905898.htm
因果関係が確立されている

  • ホウ素と骨の維持、関節の維持

Scientific Opinion on the substantiation of health claims related to boron and maintenance of bone (ID 218, 219) and maintenance of joints (ID 219, 220) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906787.htm
いずれも因果関係は確立されていない

  • Lathyrus pratensis L(キバナノレンソウ)と上部気道機能

Scientific Opinion on the substantiation of health claims related to Lathyrus pratensis L. and function of the upper respiratory tract (ID2456) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906799.htm
因果関係は確立されていない

Levisticum officinale W.D.J. Koch（ラベッジ）と利尿機能改善
Scientific Opinion on the substantiation of health claims related to Levisticum officinale W.D.J. Koch and improvement of diuretic function (ID 2292, 3420) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906832.htm
因果関係は確立されていない

  • Armoracia rusticana P. Gaertn（セイヨウワサビ）と利尿機能改善

Scientific Opinion on the substantiation of health claims related to Armoracia rusticana P. Gaertn. and improvement of diuretic function (ID2224, 2719) pursuant to Article 13 of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906937.htm
因果関係は確立されていない

  • Justicia adhatoda L.（アダトーダ）と酸化的傷害からのDNA,蛋白質、脂質の保護と上部気道機能

Scientific opinion on the substantiation of health claims related to Justicia adhatoda L. and protection of DNA, proteins and lipids from oxidative damage (ID 2508) and function of the upper respiratory tract (ID 3970) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906949.htm
いずれも因果関係は確立されていない

  • シアル酸と学習及び記憶

Scientific Opinion on the substantiation of health claims related to sialic acid and learning and memory (ID 1594) pursuant to Article13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906961.htm
因果関係は確立されていない

  • Calluna vulgaris (L.) Hull（カルーナ）と気分のバランスと睡眠導入

Scientific Opinion on the substantiation of health claims related to Calluna vulgaris (L.) Hull. and mood balance and ability to fall asleep (ID 2815) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906970.htm
因果関係は確立されていない

  • コンドロイチンとコンドロイチン硫酸と関節維持

Scientific Opinion on the substantiation of health claims related to chondroitin and chondroitin sulphate and maintenance of joints (ID 1504, 1505) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906998.htm
因果関係は確立されていない

  • Carthamus tinctorius L.（紅花）と皮膚の維持、毛髪の維持

Scientific Opinion on the substantiation of health claims related to Carthamus tinctorius L. and maintenance of skin (ID 2748) and maintenance of hair (ID 4242) pursuant to Article 13(1) of Regulation
(EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907015.htm
いずれも因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to Ocimum basilicum L. and improvement of diuretic function (ID 2314,3465) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907024.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to hyaluronic acid and maintenance of joints (ID 1572, 1731, 1932, 3132) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907054.htm
因果関係は確立されていない

  • Chenopodium quinoa L.（キノア）と毛髪の維持

Scientific Opinion on the substantiation of health claims related to Chenopodium quinoa L. and maintenance of hair (ID 2746) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907064.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to Ajuga reptans L. and sebum production (ID 2792) pursuant to Article
13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907078.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to inositol and cognitive function (ID 1588) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907088.htm
因果関係は確立されていない

緑イガイ抽出物と関節や骨や筋肉の維持
Scientific Opinion on the substantiation of health claims related to green lipped mussel extract and maintenance of joints, bone and muscles (ID 1571, 1813) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907102.htm
因果関係は確立されていない

  • Ammi visnaga (L.) Lam.（イトバドクゼリモドキ）と上部気道過敏の緩和

Scientific Opinion on the substantiation of health claims related to Ammi visnaga (L.) Lam. and relief in case of irritation in the upper respiratory tract (ID 2211) pursuant to Article 13(1) of Regulation
(EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907114.htm
因果関係は確立されていない

  • Fraxinus excelsior L.（セイヨウトネリコ）と関節及び正常体重の維持

Scientific Opinion on the substantiation of health claims related to Fraxinus excelsior L. and maintenance of joints (ID 2256) and maintenance or achievement of a normal body weight (ID 3688) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907123.htm
いずれも因果関係は確立されていない

  • Hibiscus sabdariffa L.（ローゼル）と利尿機能の改善および腸の運動機能

Scientific opinion on the substantiation of health claims related to Hibiscus sabdariffa L. and improvement of diuretic function (ID 2267,
3393) and bowel motor function (ID 3391) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907138.htm
いずれも因果関係は確立されていない

  • オリーブバイオフェノールと病原性の可能性のある腸内微生物の減少

Scientific Opinion on the substantiation of health claims related to olive biophenols and decreasing potentially pathogenic intestinal microorganisms (ID 1877) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907147.htm
因果関係は確立されていない

  • メチルスルホニルメタン単独又は塩酸グルコサミンとの組み合わせと関節維持

Scientific Opinion on the substantiation of health claims related to methylsulfonylmethane alone or in combination with glucosamine hydrochloride and maintenance of joints (ID 395, 1616, 1617) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907162.htm
因果関係は確立されていない

  • シュガーフリーチューインガムと歯や口腔の健康、歯肉や歯の保護及び強度、

歯垢の酸中和、歯ミネラル化維持、口の渇きの削減および正常体重維持
Scientific Opinion on the substantiation of health claims related to sugar free chewing gum and dental and oral health, including gum and tooth protection and strength (ID 1149), plaque acid neutralisation (ID 1150), maintenance of tooth mineralisation (ID 1151), reduction of oral dryness (ID 1240), and maintenance of the normal body weight (ID 1152) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907178.htm
正常体重維持については因果関係は確立されていない、その他は飲食後に使用することで因果関係は確立されている。窒息リスクの高い3才未満の子どもには与えない。

  • Angelica sinensis (Oliv.) Diels.と関節の維持と酸素輸送

Scientific Opinion on the substantiation of health claims related to Angelica sinensis (Oliv.) Diels. and maintenance of joints (ID 2392) and oxygen transport (ID 3845) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907190.htm
いずれも因果関係は確立されていない

  • Justicia gendarussa L.と利尿機能の改善と下部尿道炎症削減

Scientific Opinion on the substantiation of health claims related to Justicia gendarussa L. and improvement of diuretic function (ID 2455) and reduction of inflammation of the lower urinary tract (ID 2455) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907219.htm
いずれも因果関係は確立されていない

  • Helianthus tuberosus L.（キクイモ）と病原性腸内細菌の減少、乳糖分解、 正常体重への変化及び維持

Scientific opinion on the substantiation of health claims related to Helianthus tuberosus L. and decreasing potentially pathogenic intestinal microorganisms (ID 2819), breaking down lactose (ID 2819) and maintenance or achievement of a normal body weight (ID 2820) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907246.htm
いずれも因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to acacia gum and maintenance of normal blood cholesterol concentrations (ID 1976) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907260.htm
因果関係は確立されていない

Opinion on the substantiation of health claims related to alpha linolenic acid and maintenance of normal blood cholesterol concentrations (ID 493) and maintenance of normal blood pressure (ID625) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907287.htm
コレステロールに関しては1日2gの参照用量で因果関係は確立されている、血圧については因果関係は確立されていない

  • サメ軟骨と関節の維持

Scientific Opinion on the substantiation of health claims related to shark cartilage and maintenance of joints (ID 1852, 1853) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907299.htm
因果関係は確立されていない

  • ベータグルカンと正常な血中コレステロール濃度の維持、正常体重への変化又は維持

Scientific Opinion on the substantiation of health claims related to beta glucans and maintenance of normal blood cholesterol concentrations (ID 754, 755, 757, 801, 1465, 2934) and maintenance or achievement of a normal body weight (ID 820, 823) pursuant to Article13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907313.htm
コレステロールについては参照用量1日3gで因果関係は確立されている、体重に関しては因果関係は確立されていない

  • Picea abies (L.) Karsten（ドイツトウヒ）と上部気道過敏

Scientific Opinion on the substantiation of health claims related to Picea abies (L.) Karsten and relief in case of irritation in the upper respiratory tract (ID 2827, 3493, 4095) pursuant to Article
13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907325.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to soy isoflavones and maintenance of bone mineral density (ID 1655) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907369.htm
因果関係は確立されていない

  • グルコサミン単独又はコンドロイチン硫酸との組み合わせで関節の維持と炎症の削減

Scientific Opinion on the substantiation of health claims related to glucosamine alone or in combination with chondroitin sulphate and maintenance of joints (ID 1561, 1562, 1563, 1564, 1565) and reduction of inflammation (ID 1869) pursuant to Article 13(1) of Regulation(EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907380.htm
いずれも因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to dietary fibre and maintenance of normal blood cholesterol concentrations (ID 747, 750, 811) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907411.htm
食物繊維の定義が不十分

  • Corylus avellana L.（セイヨウハシバミ）と皮膚の維持

Scientific Opinion on the substantiation of health claims related to Corylus avellana L. and maintenance of skin (ID 2749) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907444.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to isomalto-oligosaccharides and maintenance of normal blood cholesterol concentrations (ID 817) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907462.htm
因果関係は確立されていない

  • 性質が明確でない微生物に関する健康強調表示

Scientific Opinion on the substantiation of health claims related to non characterised microorganisms pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907474.htm
系統の同定がなされていないので因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to taurine and protection of DNA, proteins and lipids from oxidative damage (ID 612, 1658, 1959), energy-yielding metabolism (ID 614), and delay in the onset of fatigue and enhancement of physical performance (ID 1660) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907483.htm
いずれも因果関係は確立されていない

  • Lactobacillus rhamnosus HN001 (AGAL NM97/09514)と病原性の可能性のある腸内細菌の減少

Scientific Opinion on the substantiation of health claims related to Lactobacillus rhamnosus HN001 (AGAL NM97/09514) and decreasing potentially pathogenic intestinal microorganisms (ID 908) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907568.htm
因果関係は確立されていない

レステロール濃度維持、関節維持
Scientific Opinion on the substantiation of health claims related to EPA, DHA, DPA and maintenance of normal blood pressure (ID 502), maintenance of normal HDL-cholesterol concentrations (ID 515), maintenance of normal (fasting) blood concentrations of triglycerides (ID 517), maintenance of normal LDL-cholesterol concentrations (ID 528, 698) and maintenance of joints (ID 503, 505, 507, 511, 518, 524, 526, 535, 537) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907585.htm
1日2-4gのEPAとDHAによる血中トリグリセリドへの影響、1日3gのEPAとDHAによる血圧への影響は確立されている。その他は因果関係は確立されていない

  • アップルサイダービネガー（りんご酢）と腸の運動機能

Scientific Opinion on the substantiation of health claims related to apple cider vinegar and bowel motor function (ID 1377) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907597.htm
因果関係は確立されていない

  • ベータカロテンとUV照射に関連する皮膚の生理的免疫応答

Scientific Opinion on the substantiation of health claims related to beta carotene and physiological immune responses of the skin in relation to UV radiation (sun exposure) (ID 198, 1463) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907609.htm
因果関係は確立されていない

  • エキウム油と正常血中トリグリセリド濃度の維持

Scientific Opinion on the substantiation of health claims related to echium oil and maintenance of normal blood concentrations of triglycerides (ID 548) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907623.htm
因果関係は確立されていない

  • Lactobacillus plantarum 299 (DSM 6595, 67B)と免疫系

Scientific Opinion on the substantiation of health claims related to Lactobacillus plantarum 299 (DSM 6595, 67B) and immune system (ID1077) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907647.htm
因果関係は確立されていない

  • Bifidobacterium animalis Lafti B94 (CBS118.529)と病原性の可能性のある

腸内細菌の減少
Scientific Opinion on the substantiation of health claims related to Bifidobacterium animalis Lafti B94 (CBS118.529) and decreasing potentially pathogenic intestinal microorganisms (ID 867) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907662.htm
因果関係は確立されていない

  • Lactobacillus plantarum 299v (DSM 9843)と病原性の可能性のある腸内細菌の減少

Scientific Opinion on the substantiation of health claims related to Lactobacillus plantarum 299v (DSM 9843) and decreasing potentially pathogenic intestinal microorganisms (ID 1084) pursuant to Article
13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907674.htm
因果関係は確立されていない

  • 柿と視覚の維持

Scientific Opinion on the substantiation of health claims related to kaki fruit and maintenance of vision (ID 1261) pursuant to Article13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907683.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to calcium and vitamin D and maintenance of bone (ID 350) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907698.htm
カルシウムとビタミンDは正常な骨の維持に必要である

  • 発酵乳製品と病原性の可能性のある腸内細菌の減少

Scientific Opinion on the substantiation of health claims related to fermented dairy products and decreasing potentially pathogenic intestinal microorganisms (ID 1376) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907717.htm
因果関係は確立されていない

  • Lactobacillus casei F19 (LMG P-17806)と腸の運動機能

Scientific Opinion on the substantiation of health claims related to Lactobacillus casei F19 (LMG P-17806) and bowel motor function (ID893) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907785.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to gamma linolenic acid and reduction of inflammation (ID 1772) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907797.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to lactase enzyme and breaking down lactose (ID 1697, 1818) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907809.htm
ラクターゼ酵素は乳糖分解に貢献する

  • リン脂質とDNA、蛋白質、脂質の酸化的傷害からの保護、記憶、学習、集中力及び神経系機能

Scientific Opinion on the substantiation of health claims related to phospholipids and protection of DNA, proteins and lipids from oxidative damage (ID 1834), memory, learning capacity and attention, and function of the nervous system (ID 1835) pursuant to Article13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907823.htm
いずれも因果関係は確立されていない

  • Lactobacillus reuteri ATCC 55730と病原性の可能性のある腸内細菌の減少

Scientific Opinion on the substantiation of health claims related to Lactobacillus reuteri ATCC 55730 and decreasing potentially pathogenic intestinal microorganisms (ID 904) pursuant to Article
13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907835.htm
因果関係は確立されていない

  • Lactobacillus johnsonii BFE 6128と病原性の可能性のある腸内細菌の減少

Scientific Opinion on the substantiation of health claims related to Lactobacillus johnsonii BFE 6128 and decreasing potentially pathogenic intestinal microorganisms (ID 989) pursuant to Article
13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907847.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to glucomannan and maintenance of normal blood cholesterol concentrations (ID 836, 1560) pursuant to Article 13(1) of Regulation
(EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907862.htm
グルコマンナンを定期的に食べると正常血中コレステロール濃度の維持に役立つ

  • ケイ素とマクロファージ活性化と循環リンパ球の増加

Scientific Opinion on the substantiation of health claims related to silicon and stimulating macrophages and increasing circulating lymphocytes (ID 358) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907874.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to copper and protection of DNA, proteins and lipids from oxidative damage (ID 263, 1726), function of the immune system (ID 264), maintenance of connective tissues (ID 265, 271, 1722), energy-yielding metabolism (ID 266), function of the nervous system (ID 267), maintenance of skin and hair pigmentation (ID 268, 1724), iron transport (ID 269, 270, 1727), cholesterol metabolism (ID 369), and glucose metabolism (ID 369) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907888.htm
コレステロールとグルコース代謝以外については因果関係は確立されている

  • 鉄と赤血球細胞やヘモグロビンの生成、酸素輸送、エネルギーを発生する代謝、免疫系機能、認知機能、細胞分割

Scientific Opinion on the substantiation of health claims related to iron and formation of red blood cells and haemoglobin (ID 249, ID 1589), oxygen transport (ID 250, ID 254, ID 256), energy-yielding metabolism (ID 251, ID 1589), function of the immune system (ID 252, ID 259), cognitive function (ID 253) and cell division (ID 368) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907900.htm
因果関係は確立されている

  • イプリフラボンと骨ミネラル密度の維持

Scientific Opinion on the substantiation of health claims related to ipriflavone and maintenance of bone mineral density (ID 1872) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907912.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to iodine and thyroid function and production of thyroid hormones (ID 274), energy-yielding metabolism (ID 274), maintenance of vision (ID 356), maintenance of hair (ID 370), maintenance of nails (ID 370), and maintenance of skin (ID 370) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907924.htm
視覚と毛髪と爪の他は因果関係は確立されている

  • γアミノ酪酸（GABA）と認知機能

Scientific Opinion on the substantiation of health claims related to gamma-aminobutyric acid and cognitive function (ID 1768) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907936.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to folate and blood formation (ID 79), homocysteine metabolism (ID 80), energy-yielding metabolism (ID 90), function of the immune system (ID 91), function of blood vessels (ID 94, 175, 192), cell division (ID 193), and maternal tissue growth during pregnancy (ID 2882) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907948.htm
エネルギーを発生する代謝と血管機能以外については因果関係は確立されている

Scientific Opinion on the substantiation of health claims related to linoleic acid and maintenance of normal blood cholesterol concentrations (ID 489) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907970.htm
1日10gを参照用量に、因果関係は確立されている

  • チアミンとエネルギーを発生する代謝、心機能、神経系機能、骨の維持、歯の維持、髪の維持、爪の維持、皮膚の維持

Scientific Opinion on substantiation of health claims related to thiamine and energy-yielding metabolism (ID 21, 24, 28), cardiac function (ID 20), function of the nervous system (ID 22, 27), maintenance of bone (ID 25), maintenance of teeth (ID 25), maintenance of hair (ID 25), maintenance of nails (ID 25), maintenance of skin (ID 25) pursuant to Article 13(1) of Regulation
(EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902907982.htm
エネルギーを発生する代謝、心機能、神経系機能については因果関係は確立されている。
骨の維持、歯の維持、髪の維持、爪の維持、皮膚の維持については因果関係は確立されていない

  • Lactobacillus paracasei 8700:2 (DSM 13434, 240HI) と病原性の可能性のある腸内細菌の減少

Scientific Opinion on the substantiation of health claims related to Lactobacillus paracasei 8700:2 (DSM 13434, 240HI) and decreasing potentially pathogenic intestinal microorganisms (ID 1074) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902908081.htm
因果関係は確立されていない

  • Lactobacillus gasseri CECT5714 と Lactobacillus coryniformis CECT5711と病原性の可能性のある腸内細菌の減少と腸輸送改善

Scientific Opinion on the substantiation of health claims related to “ Lactobacillus gasseri CECT5714 and Lactobacillus coryniformis CECT5711 ” and decreasing potentially pathogenic intestinal microorganisms and improvement of intestinal transit (ID 937) pursuant to Article 13 of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902908108.htm
いずれも因果関係は確立されていない

  • グルタミンと免疫系の健康、腸上皮の健全性と正常な腸透過性

Scientific Opinion on the substantiation of health claims related to glutamine and immune health (ID 733) and integrity of the intestinal lining and normal intestinal permeability (ID 1602) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902908137.htm
いずれも因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to isoleucine-proline-proline (IPP) and valine-proline-proline (VPP) and maintenance of normal blood pressure (ID 615, 661, 1831, 1832, 2891), and maintenance of the elastic properties of the arteries (ID 1832) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902908265.htm
データ不十分及び因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to astaxanthin and maintenance of joints, tendons, and connective tissue (ID 1918, 1978, 3142), protection of DNA, proteins and lipids from oxidative damage (ID 1449, 3141), maintenance of visual acuity (ID 1448), maintenance of blood cholesterol concentrations and maintenance of low plasma concentrations of C-reactive protein (ID
1450) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902908277.htm
いずれも因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to zinc and function of the immune system (ID 291, 1757), DNA synthesis and cell division (ID 292, 1759), protection of DNA, proteins and lipids from oxidative damage (ID 294, 1758), maintenance of bone (ID 295, 1756), cognitive function (ID 296), fertility and reproduction (ID 297, 300), reproductive development (ID 298), muscle function (ID 299), metabolism of fatty acids (ID 302), maintenance of joints (ID 305), function of the heart and blood vessels (ID 306), prostate function (ID 307), thyroid function (ID 308), acid-base metabolism (ID 360), vitamin A metabolism (ID 361) and maintenance of vision (ID
361) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902908313.htm
生殖系発達については子どもの発育関連なので対象外。筋機能、関節維持、心や血管機能、前立腺機能については因果関係は確立されていない。甲状腺機能についてはデータが不十分。その他については因果関係は確立されている。

Scientific Opinion on the substantiation of health claims related to vitamin D and maintenance of bone and teeth (ID 150, 151, 158), absorption and utilisation of calcium and phosphorus and maintenance of normal blood calcium concentrations (ID 152, 157), cell division (ID 153), and thyroid function (ID 156) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902908675.htm
甲状腺機能以外については因果関係は確立されている

Scientific Opinion on the substantiation of health claims related to vitamin B12 and red blood cell formation (ID 92, 101), cell division (ID 93), energy-yielding metabolism (ID 99, 190) and function of the immune system (ID 107) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902905898.htm
因果関係は確立されている

  • マンガンとDNA、蛋白質、脂質の酸化的傷害からの保護、骨の維持、エネルギーを発生する代謝、認知機能

Scientific Opinion on the substantiation of health claims related to manganese and protection of DNA, proteins and lipids from oxidative damage (ID 309), maintenance of bone (ID 310), energy-yielding metabolism (ID 311), and cognitive function (ID 340) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902905961.htm
認知機能の他は因果関係は確立されている

  • ビタミンAと細胞分化、免疫系機能、皮膚と粘膜の維持、視覚維持、骨維持、 歯の維持、毛髪維持、爪維持、鉄代謝、DNA、蛋白質、脂質の酸化的傷害からの保護

Scientific Opinion on the substantiation of health claims related to vitamin A and cell differentiation (ID 14), function of the immune system (ID 14), maintenance of skin and mucous membranes (ID 15, 17), maintenance of vision (ID 16), maintenance of bone (ID 13, 17), maintenance of teeth (ID 13, 17), maintenance of hair (ID 17), maintenance of nails (ID 17), metabolism of iron (ID 206), and protection of DNA, proteins and lipids from oxidative damage (ID 209) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906133.htm
骨維持、歯の維持、毛髪維持、爪維持、DNA、蛋白質、脂質の酸化的傷害からの保護については因果関係は確立されていない。その他については因果関係は確立されている

  • Cyamopsis tetragonoloba (L.) Taubert（グアー豆）と正常定住への変化や維

持、長期の正常血糖値維持
Scientific opinion on the substantiation of health claims related to Cyamopsis tetragonoloba (L.) Taubert and maintenance or achievement of a normal body weight (ID 2428) and long-term maintenance of normal blood glucose concentrations (ID 2429) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906176.htm
いずれも因果関係は確立されていない

  • Daucus carota L.（ニンジン）と視覚維持

Scientific opinion on the substantiation of health claims related to Daucus carota L. and maintenance of vision (ID 2431) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906198.htm
因果関係は確立されていない

  • Equisetum arvense L.（スギナ）と身体の活性化、皮膚の維持、毛髪の維持、骨の維持、正常体重への変化や維持

Scientific opinion on the substantiation of health claims related to Equisetum arvense L. and invigoration of the body (ID 2437), maintenance of skin (ID 2438), maintenance of hair (ID 2438), maintenance of bone (ID 2439), and maintenance or achievement of a normal body weight (ID 2783) pursuant to Article 13 of Regulation(EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906210.htm
いずれも因果関係は確立されていない

  • Viola tricolour L.（パンジー）と上部気道過敏緩和

Scientific Opinion on the substantiation of health claims related to Viola tricolour L. and relief in case of irritation in the upper respiratory tract (ID 2356) pursuant to Article 13(1) of Regulation
(EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906222.htm
因果関係は確立されていない

  • Undaria pinnatifida (Harvey) Suringar（ワカメ）と正常体重への変化や維持

Scientific opinion on the substantiation of health claims related to Undaria pinnatifida (Harvey) Suringar and maintenance or achievement of a normal body weight (ID 2345) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906241.htm
因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to
5 hydroxytryptophan and enhancement of mood (ID 1575) and attention (ID 1828) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906297.htm
いずれも因果関係は確立されていない

  • Theobroma cacao L.（カカオ）と正常体重への変化や維持

Scientific Opinion on the substantiation of health claims related to Theobroma cacao L. and maintenance or achievement of a normal body weight (ID 2724) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906478.htm
因果関係は確立されていない

  • Fagopyrum esculentum Moench.（ソバ）と上部気道機能

Scientific Opinion on the substantiation of health claims related to Fagopyrum esculentum Moench. and function of the upper respiratory tract (ID 2442) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906503.htm
因果関係は確立されていない

  • ビタミンKと骨の維持、血液凝固、心と血管機能

Scientific Opinion on the substantiation of health claims related to vitamin K and maintenance of bone (ID 123, 127, 128, and 2879), blood coagulation (ID 124 and 126), and function of the heart and blood vessels (ID 124, 125 and 2880) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906523.htm
骨の維持、血液凝固については因果関係は確立されている。
心と血管機能については根拠不十分。

  • リンと細胞膜機能、エネルギーを発生させる代謝、骨と歯の維持

Scientific Opinion on the substantiation of health claims related to phosphorus and function of cell membranes (ID 328), energy-yielding metabolism (ID 329, 373) and maintenance of bone and teeth (ID 324,327) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906555.htm
因果関係は確立されている。

Scientific Opinion on the substantiation of health claims related to pantothenic acid and energy-yielding metabolism (ID 56, 59, 60, 64, 171, 172, 208), mental performance (ID 57), maintenance of bone (ID 61), maintenance of teeth (ID 61), maintenance of hair (ID 61), maintenance of skin (ID 61), maintenance of nails (ID 61) and synthesis and metabolism of steroid hormones, vitamin D and some neurotransmitters (ID 181) pursuant to Article 13(1) of Regulation
(EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906567.htm
骨・歯・毛髪・皮膚・爪の維持以外は因果関係は確立されている。

  • ビタミンB6と蛋白質とグリコーゲンの代謝、神経系機能、赤血球合成、免疫機能、ホルモン活性制御、精神能力

Scientific Opinion on the substantiation of health claims related to vitamin B6 and protein and glycogen metabolism (ID 65, 70, 71), function of the nervous system (ID 66), red blood cell formation (ID 67, 72, 186), function of the immune system (ID 68), regulation of hormonal activity (ID 69) and mental performance (ID 185) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906579.htm
過剰摂取による精神能力向上については範囲外。その他については因果関係は確立されている

  • セレンとDNA、蛋白質、脂質の酸化的傷害からの保護、免疫系機能、甲状腺機能、心や血管機能、前立腺機能、認知機能、精子形成

Scientific Opinion on the substantiation of health claims related to selenium and protection of DNA, proteins and lipids from oxidative damage (ID 277, 283, 286, 1289, 1290, 1291, 1293, 1751), function of the immune system (ID 278), thyroid function (ID 279, 282, 286, 1289, 1290, 1291, 1293), function of the heart and blood vessels (ID 280), prostate function (ID 284), cognitive function (ID 285) and spermatogenesis (ID 396) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906597.htm
認知機能と前立腺機能については因果関係は確立されていない。心と血管機能については根拠不十分。その他は因果関係は確立されている。

  • ビタミンCとDNA、蛋白質、脂質の酸化的傷害からの保護、ルテインの抗酸化機能、視覚維持、コラーゲン形成、神経系機能、免疫系機能、極めて激しい運動の間及びその後の免疫系機能、非ヘム鉄の吸収、エネルギーを発生する代謝、 上部気道過敏緩和

Scientific Opinion on the substantiation of health claims related to vitamin C and protection of DNA, proteins and lipids from oxidative damage (ID 129, 138, 143, 148), antioxidant function of lutein (ID 146), maintenance of vision (ID 141, 142), collagen formation (ID 130, 131, 136, 137, 149), function of the nervous system (ID 133), function of the immune system (ID 134), function of the immune system during and after extreme physical exercise (ID 144), non-haem iron absorption (ID 132, 147), energy-yielding metabolism (ID 135), and relief in case of irritation in the upper respiratory tract (ID 1714,
1715) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906649.htm
ルテインの抗酸化機能と上部気道過敏緩和については因果関係は確立されていない。視覚維持については根拠不十分。その他については因果関係は確立されている。

Scientific opinion on the substantiation of health claims related to Tussilago farfara L. and function of the upper respiratory tract and immune health (ID 2497) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906674.htm
いずれも因果関係は確立されていない

Scientific Opinion on the substantiation of health claims related to niacin and energy-yielding metabolism (ID 43, 49, 54), function of the nervous system (ID 44, 53), maintenance of the skin and mucous membranes (ID 45, 48, 50, 52), maintenance of normal LDL-cholesterol, HDL cholesterol and triglyceride concentrations (ID 46), maintenance of bone (ID 50), maintenance of teeth (ID 50), maintenance of hair (ID 50, 2875) and maintenance of nails (ID 50, 2875) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906691.htm
骨、歯、毛髪、爪の維持については因果関係は確立されていない。ナイアシンの過剰摂取によるコレステロールなどの維持は範囲外。その他については因果関係は確立されている。

  • ビオチンとエネルギーを発生する代謝、主要栄養素の代謝、皮膚と粘膜の維持、毛髪維持、神経系機能

Scientific Opinion on the substantiation of health claims related to biotin and energy-yielding metabolism (ID 114, 117), macronutrient metabolism (ID 113, 114, 117), maintenance of skin and mucous membranes (ID 115), maintenance of hair (ID 118, 2876) and function of the nervous system (ID 116) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906703.htm
因果関係は確立されている。

  • Aegopodium podagraria L.（イワミツバ）と正常体重への変化や維持

Scientific Opinion on the substantiation of health claims related to Aegopodium podagraria L. and maintenance or achievement of a normal body weight (ID 2384) pursuant to Article 13 (1) of Regulation (EC) No 1924/2006
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902906760.htm
因果関係は確立されていない