Trigger in heparin deaths confirmed
Published online 24 April 2008 | Nature | doi:10.1038/news.2008.774
Rachel Courtland
http://www.nature.com/news/2008/080424/full/news.2008.774.html
・問題のヘパリンからの過硫酸化ヘパリンの同定
Guerrini, M., et al. Nat. Biotech. 26, doi:10.1038/nbt1407 (2008)
Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events
http://www.nature.com/nbt/extra/nbt1407.pdf
（オープンアクセス）
http://www.nature.com/nbt/extra/nbt1407-S1.pdf
補遺
・過硫酸化ヘパリンのブタでのアレルギー症状誘発
Kishimoto, T.K. et al. New England Journ. Med. 358,
doi:10.1056/NEJMoa0803200 (2008)
Contaminated Heparin Associated with Adverse Clinical Events and Activation of the Contact System
http://content.nejm.org/cgi/content/full/NEJMoa0803200
（こっちはオープンアクセスではないような）
